Utilization of social capital in establishing a social safety net for children
Department of Child Psychology and Education
Prof. Yanghee Lee
Dr. Sangwon Kim
Big data analytics for identifying student usage patterns and instructional strategies in an online learning platform
Education
Prof. KIM, DONGHO
A Research Team led by Professor Sungho Park Designed Complex Au Nanorings with Interwined Triple Rings in a Single Entity to Amplify the Efficacy of Near-field focusing in a Solution Phase - Expected to be used in various fields such as nano, optical, sensor, bio, etc. - Selected as a cover page for the JACS As global interest in sustainable energy increases, the importance of developing materials that can efficiently concentrates sunlight is increasing. Among them, plasmonic nanoparticles are essential materials for various application studies that require efficient conversion of light energy into electric energy or thermal energy, including applied research using light energy because they can amplify interaction with light. The research team led by Sungho Park, professor of chemistry at Sungkyunkwan University (first author: Sungjae Yoo) is actively working on developing nanoframe materials with maximized structural complexity to increase the physical and chemical properties of plasmonic nanoparticles. The team designed complex Au nanorings with interwined triple rings in a single entity to amplify the efficacy of near-field focusing in a solution phase for the first time. Using the newly developed chemical reactions, the researchers rationally designed the multiple step synthesis method to control the internal nanogap distance of the triple nanoring structure and refine the shape of the frame structure, and further integrate four nanoring structures of different sizes inside a single particle. The synthesized triple ring structure exhibited an enormously large enhancement factor (∼109) of Raman signals, which is more than 100 times compared to conventional plasmonic gold particles, while simultaneously showing high signal reproducibility and stability regardless of the direction of light incident in a single nanoparticle. This is an innovative material that presents a new paradigm in the field of plasmonic particles, recognized for its significant contribution to the commercialization of Raman optical analysis techniques. Professor Sungho Park said “This study presents a methodology for controlling and analyzing nanoparticles and is expected to be widely used in various field such as nano, optical, sensor, bio, etc. This work was supported by the National Research Foundation of Korea (NRF) and was selected as the cover page of the Journal of the American Chemistry Society (Impact Factor: 15.419) in the field of chemistry and published online on August 9 (Mon). ※ Title of paper : Au Nanorings with Intertwined Triple rings
2021-08-31
A Research Team Led by Prof. Dohyun Ryu, Developed the Synthetic Method of Chiral Trisubstituted Epoxides [Image 1] Dohyun Ryu (Professor of Chemistry), Dongguk Nam (Doctoral Program) A research team led by Prof Dohyun Ryu (1st author: Dongguk Nam) succeed in developing the synthetic method of chiral trisubstituted epoxides using boron-Lewis acid catalyst. The chiral epoxide compounds have received much attention from academia and industry as a key intermediate in the synthesis of biologically active molecules such as natural and pharmaceutical products and the catalyst synthesis method won the Nobel Prize in Chemistry in 2001. Until recently, leading overseas research groups have published research results on the development of synthetic methods, but no examples of asymmetric synthesis of trisubstituted epoxides using diazoesters. Thus, the research team synthesized chiral trisubstituted epoxides with high yield, stereoselectivity, and high optical selectivity through Darzens-type reaction using boron-Lewis acid catalyst. The developed reaction is very efficient in terms of atom economy and eco-friendliness because it uses simple structural starting materials and produces by-products of nitrogen gas only. [Image 2] Efficient asymmetric synthesis of trisubstituted epoxide using Darzens-type reaction Professor Ryu said “The synthesis of chiral trisubstituted epoxide compounds using the Dazens reaction is a task that has not been solved in the past 20 years. The significance of this study is that it first synthesized trisubstituted epoxide with high yield and stereoselectivity using catalysts and presented various applications.” This work was supported by National Research Foundation of Korea (NRF) grants funded by the Korean government (MSIP) and published in world-renewed journal in chemistry, Angewandte Chemie International Edition (IF = 15.34)’s early view on August 4 (Wed). ※ https://doi.org/10.1002/anie.202108454
2021-08-23
Sungkyunkwan University’s Research Team Verified the Effectiveness of CaronBio’s Hair Loss Prevention Hair Care Products -Published in the international journal, Pharmaceutics Study shows that the main ingredient of hair loss shampoo developed in Korea inducing the growth of hair follicle dermal papilla cells (HFDPC). A research team led by Professor Seok-Ho Bang, School of Chemical Engineering at Sungkyunkwan University (Jiyoo Hyun, Jisoo Lim, Sungwon Kim and Inwoo Seo), recently published a paper in the international journal, Pharmaceutics. According to the paper, the experimental sample contains high concentrations of chlorogenic acid and Umbelliferon. Chlorogenic acid is a type of polyphenol compound that inhibits cholesterol biosynthesis in vivo, antioxidants, and anticancer. Umpeliperone has antibacterial and inflammatory effects. Treatment of the experimental samples used in the study to the HFDPC resulted in increased growth factor population due to activation of beta-catenin proteins. It also showed significant improvements in angiogenesis in the transportation of growth periods in HFDPC. In addition, it has been found that the proliferation of keratinocytes and the development of differentiation facilitates the transition from tissue to growth. The research team explained, “The experimental samples in this study induce improved angiogenesis and enhance tube formation of endothelial cells. Additionally, as the proliferation of dead keratin cells, it promotes hair growth by inducing the transition from tissue to growth. The cause of hair loss varies from hormones, medication, and nutritional deficiency. Hair loss can be restored by hair follicle regeneration and is affected by dead keratin cells, fibrocyte and dermal papillae cells. The antioxidant and anti-inflammatory effects of the main ingredients of Carombio C3 Sampoo and Tonic has already been verified through invitro test by the Korea Insititute of Dermatological Sciences. In addition, in the safety clinical trial of the German Derma Test, it was rated the highest score (5 stars) and was verified its effectiveness of hair loss prevention. Original Article: http://news.heraldcorp.com/view.php?ud=20210817000185
2021-08-18
